Description

4-(8-Hydroxy-1,4-Dioxa-Spiro[4.5]Dec-8-Yl)-Benzonitrile is a high-value, multifunctional organic intermediate featuring a unique spirocyclic acetal structure combined with a benzonitrile moiety. This compound matters for its role as a versatile building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. Industries that require sophisticated chiral synthons for developing new active ingredients, such as pharmaceutical R&D and specialty chemical manufacturing, are the primary users of this material.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides, leveraging its spirocyclic structure for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Academic & Industrial R&D: A valuable tool for chemists in both university and corporate settings exploring new synthetic methodologies and compound libraries.

Basic Information

Item	Details
Product Name	4-(8-Hydroxy-1,4-Dioxa-Spiro[4.5]Dec-8-Yl)-Benzonitrile
CAS No.	137464-95-0
Molecular Formula	C15H17NO3
Molecular Weight	259.30 g/mol
Synonyms	4-(8-Hydroxy-1,4-dioxaspiro[4.5]dec-8-yl)benzonitrile; 4-(8-Hydroxy-1,4-dioxaspiro[4.5]decan-8-yl)benzonitrile; 8-(4-Cyanophenyl)-1,4-dioxaspiro[4.5]decan-8-ol; 4-(8-Hydroxy-1,4-dioxa-spiro[4.5]dec-8-yl)-benzonitrile; 137464-95-0; Spirocyclic benzonitrile derivative; 8-Hydroxy-8-(4-cyanophenyl)-1,4-dioxaspiro[4.5]decane
EINECS	Contact for details

Quality Control

Our 4-(8-Hydroxy-1,4-Dioxa-Spiro[4.5]Dec-8-Yl)-Benzonitrile is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (by HPLC), identity confirmation, and impurity profiles. Our quality commitment aligns with the standards required for advanced chemical intermediates in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.