Description

(2E)-3-(4-Methoxyphenyl)-1-(Thiophen-2-Yl)Prop-2-En-1-One is a high-purity, synthetic chalcone derivative characterized by its distinct molecular structure featuring methoxyphenyl and thiophene moieties. This compound is a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, valued for its role in constructing complex molecules. It is primarily needed by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and central nervous system disorders.
• Agrochemical Research: Used as a building block for developing new pesticides and herbicides, leveraging its bioactive chalcone scaffold.
• Organic Light-Emitting Diodes (OLEDs): Acts as a core component in the research and development of organic electronic materials due to its conjugated system.
• Chemical Synthesis: A versatile starting material for Michael additions, cyclizations, and other reactions to create heterocyclic compounds and complex molecular architectures.
• Material Science: Investigated for use in nonlinear optical (NLO) materials and as a monomer for specialty polymers.
• Flavor & Fragrance Industry: Potential use as an intermediate for synthesizing specific aroma chemicals, given its structural features.

Basic Information

Product Name	(2E)-3-(4-Methoxyphenyl)-1-(Thiophen-2-Yl)Prop-2-En-1-One
CAS No.	137444-51-0
Molecular Formula	C14H12O2S
Molecular Weight	244.31 g/mol
Synonyms	1-(2-Thienyl)-3-(4-methoxyphenyl)-2-propen-1-one; 3-(4-Methoxyphenyl)-1-(2-thienyl)-2-propen-1-one; 2-Propen-1-one, 1-(2-thienyl)-3-(4-methoxyphenyl)-, (2E)-; 4-Methoxychalcone thiophene derivative; (E)-3-(4-Methoxyphenyl)-1-(thiophen-2-yl)prop-2-en-1-one; 1-(Thiophen-2-yl)-3-(4-methoxyphenyl)prop-2-en-1-one; Thiophene chalcone derivative; p-Methoxyphenyl 2-thienyl ketone ethylene
EINECS	Contact for details

Quality Control

Our (2E)-3-(4-Methoxyphenyl)-1-(Thiophen-2-Yl)Prop-2-En-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	105 - 110 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.