Description

3-Pyridinecarboxylic Acid, 2,6-Bis(Trifluoromethyl)-, Methyl Ester is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring two trifluoromethyl groups, imparts significant electronic and steric properties, making it indispensable for creating complex molecules with tailored functionalities. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis, enabling novel synthetic transformations.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, or organic electronic materials due to its electron-withdrawing character.
• Chemical Biology Probes: Utilized to create labeled compounds or probes for studying biological mechanisms and pathways.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 2,6-Bis(Trifluoromethyl)-, Methyl Ester
CAS No.	137144-34-4
Molecular Formula	C10H5F6NO2
Molecular Weight	285.14 g/mol
Synonyms	Methyl 2,6-Bis(trifluoromethyl)nicotinate; 2,6-Bis(trifluoromethyl)nicotinic Acid Methyl Ester; Methyl 2,6-Bis(trifluoromethyl)-3-pyridinecarboxylate; 3-Pyridinecarboxylic Acid, 2,6-Bis(trifluoromethyl)-, Methyl Ester; 2,6-Bis(trifluoromethyl)pyridine-3-carboxylic Acid Methyl Ester; Methyl 2,6-Di(trifluoromethyl)nicotinate; Nicotinic Acid, 2,6-Bis(trifluoromethyl)-, Methyl Ester
EINECS	Contact for details

Quality Control

Our production of 3-Pyridinecarboxylic Acid, 2,6-Bis(trifluoromethyl)-, Methyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and scale-up applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.