Description

Carbamic Acid, [(Tetrahydro-2H-Pyran-2-Yl)Oxy]-, Ethyl Ester (9Ci) is a specialized organic compound featuring a carbamate ester functional group protected by a tetrahydropyranyl (THP) moiety. This structure is of significant value as a versatile building block and protecting group reagent in advanced synthetic chemistry. It is primarily utilized by pharmaceutical R&D and fine chemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and agrochemical intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Protecting Group Chemistry: The THP-protected carbamate group is used to temporarily mask amine or alcohol functionalities during complex organic syntheses.
• Agrochemical Research: Employed in the development and production of advanced pesticides, herbicides, and plant growth regulators.
• Peptide & Nucleotide Chemistry: Used in the synthesis of modified peptides and nucleotide analogs where protected amine groups are required.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory research in organic and medicinal chemistry laboratories.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke production projects.

Basic Information

Product Name	Carbamic Acid, [(Tetrahydro-2H-Pyran-2-Yl)Oxy]-, Ethyl Ester (9Ci)
CAS No.	136775-09-2
Molecular Formula	C8H15NO4
Molecular Weight	189.21 g/mol
Synonyms	Ethyl N-[(Tetrahydro-2H-pyran-2-yl)oxy]carbamate; Ethyl (Tetrahydro-2H-pyran-2-yloxy)carbamate; THP-protected Ethyl Carbamate; O-(Tetrahydro-2H-pyran-2-yl) Ethyl Carbamate; Carbamic acid, O-(tetrahydro-2H-pyran-2-yl)-, ethyl ester; Ethyl O-(tetrahydropyran-2-yl)carbamate; N-(Tetrahydro-2-pyranyloxy)urethane
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [(Tetrahydro-2H-Pyran-2-Yl)Oxy]-, Ethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.