Description

Butanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-4-Hydroxy-, Methyl Ester, (3S)- is a high-purity, chiral synthetic intermediate of significant importance in advanced pharmaceutical manufacturing. This compound, with CAS number 136703-59-8, is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those requiring specific stereochemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development and production of peptide-based therapeutics and other specialized drugs.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Peptide Synthesis: Used in the preparation of protected amino acid derivatives for solid-phase and solution-phase peptide chemistry.
• Protease Inhibitor Research: Serves as a precursor in the development of enzyme inhibitors targeting specific proteases.
• Chemical Biology & Medicinal Chemistry: Employed in research for creating novel molecular scaffolds and probing biological pathways.
• Process Development & Scale-up: Utilized in optimizing synthetic routes from laboratory scale to commercial production.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects.

Basic Information

Product Name	Butanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-4-Hydroxy-, Methyl Ester, (3S)-
CAS No.	136703-59-8
Molecular Formula	C11H21NO6
Molecular Weight	263.29 g/mol
Synonyms	(3S)-3-[(tert-Butoxycarbonyl)amino]-4-hydroxybutanoic acid methyl ester; Methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-hydroxybutanoate; Boc-L-Homoserine(OMe); Boc-Hse(OMe)-OH; Boc-Homoserine methyl ester; (S)-Methyl 3-((tert-butoxycarbonyl)amino)-4-hydroxybutanoate; 3-[(tert-Butoxycarbonyl)amino]-4-hydroxybutyric acid methyl ester, (3S)-
EINECS	Contact for details

Quality Control

Our Butanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-4-Hydroxy-, Methyl Ester, (3S)- is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.