Description

D-Alanine, (1R)-1-Carboxyethyl Ester (9Ci) is a chiral, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This high-purity building block is essential for the development of novel peptides, enzyme inhibitors, and other bioactive molecules where stereochemical control is paramount. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate the D-alanine moiety into complex target structures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly antibiotics, enzyme inhibitors, and peptide-based therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce the D-alanine residue, which can confer metabolic stability and alter biological activity in synthetic peptides.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and as a standard in analytical method development for chiral separation techniques.
• Agrochemical Development: Serves as a building block for synthesizing chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Fine Chemical Synthesis: Utilized in asymmetric synthesis and catalysis to construct complex molecules for flavors, fragrances, and advanced materials.

Basic Information

Product Name	D-Alanine, (1R)-1-Carboxyethyl Ester (9Ci)
CAS No.	136577-07-6
Molecular Formula	C5H9NO4
Molecular Weight	147.13 g/mol
Synonyms	D-Alanine ethyl ester; (R)-2-Aminopropionic acid ethyl ester; Ethyl D-alaninate; Ethyl (R)-2-aminopropanoate; D-2-Aminopropionic acid ethyl ester; (R)-Ethyl alaninate; Alanine, D-, ethyl ester; D-Alanine ethyl ester hydrochloride (related salt form)
EINECS	Contact for details

Quality Control

Our D-Alanine, (1R)-1-Carboxyethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (D-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.