Description

4,4-Bis(Diethyl)Phosphono Butanoic Acid is a specialized organophosphorus compound featuring both phosphonate and carboxylic acid functional groups. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules, particularly in the development of advanced materials and pharmaceuticals. It is primarily sought by R&D chemists and process engineers in the fine chemical, agrochemical, and pharmaceutical industries for applications requiring precise molecular modification.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting bone-related disorders or requiring phosphonate-based bioisosteres.
• Agrochemical Synthesis: Used as a precursor for developing new-generation herbicides, plant growth regulators, and fungicides with enhanced efficacy.
• Ligand and Chelating Agent: Serves as a versatile ligand for metal catalysis or a chelating agent in various chemical processes and material formulations.
• Flame Retardant Additive: Incorporated as a reactive intermediate in the production of phosphorus-containing flame retardants for polymers and textiles.
• Material Science Research: Employed in the development of functionalized surfaces, metal-organic frameworks (MOFs), and other advanced materials.
• Cross-coupling Reactions: Acts as a reagent in palladium-catalyzed cross-coupling reactions to introduce phosphonate groups into organic molecules.

Basic Information

Product Name	4,4-Bis(Diethyl)Phosphono Butanoic Acid
CAS No.	136496-88-3
Molecular Formula	C12H26O7P2
Molecular Weight	344.28 g/mol
Synonyms	4,4-Bis(diethylphosphono)butanoic Acid; Butanoic acid, 4,4-bis(diethylphosphono)-; Diethyl (3-carboxypropyl)phosphonate; 4,4-Bisphosphonobutanoic Acid Diethyl Ester; 4-(Diethoxyphosphoryl)-4-(phosphono)butanoic Acid Diethyl Ester; (4-Carboxybutyl)phosphonic Acid Diethyl Ester; P,P'-(1,4-Dioxo-1,4-butanediyl)bis-P,P-diethylphosphonic Acid; Tetraethyl 4-Carboxy-1,1,4,4-butanetetraylbis(phosphonate)
EINECS	Contact for details

Quality Control

Every batch of 4,4-Bis(Diethyl)Phosphono Butanoic Acid is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and titration methods, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee product integrity and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.