Description

Quinaldic Acid Succinimide Ester is a specialized chemical reagent primarily used as a derivatization agent for analytical chemistry. This compound is valued for its role in enhancing the detection and quantification of target analytes, particularly in sensitive chromatographic and spectroscopic methods. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, agrochemical, and life science sectors seeking precise analytical results.

Application

• Derivatization Agent for HPLC Analysis: Used to tag and improve the chromatographic separation, detection sensitivity, and stability of compounds containing carboxylic acid or amine groups.
• Fluorescent Labeling Reagent: Employed in the preparation of fluorescent derivatives for sensitive detection in bioanalytical assays and diagnostic research.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex molecules for drug discovery and development programs.
• Proteomics and Metabolomics Research: Utilized in sample preparation workflows for mass spectrometry-based analysis to identify and quantify proteins or metabolites.
• Quality Control and Impurity Profiling: Applied in the analysis of raw materials, active pharmaceutical ingredients (APIs), and finished products to ensure purity and compliance.
• Chemical Biology Probes: Acts as a reactive handle for modifying biomolecules to study biological processes and interactions.

Basic Information

Product Name	Quinaldic Acid Succinimide Ester
CAS No.	136465-99-1
Molecular Formula	C₁₄H₁₀N₂O₄
Molecular Weight	270.24 g/mol
Synonyms	2-Quinaldic Acid N-Hydroxysuccinimide Ester; Quinaldic Acid NHS Ester; N-(2-Quinolylcarbonyloxy)succinimide; 2-Quinolinecarboxylic Acid, 2,5-Dioxo-1-pyrrolidinyl Ester; 1-[(2-Quinolinylcarbonyl)oxy]-2,5-pyrrolidinedione; Quinaldyl-NHS; QA-NHS; Quinaldic Acid Active Ester
EINECS	Contact for details

Quality Control

Our Quinaldic Acid Succinimide Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for identity confirmation, to ensure it meets the high standards required for research and analytical applications. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.