Description

Methyl 2-Amino-3-(Naphthalen-1-Yl)Propanoate CAS NO 136375-70-7 is a specialized naphthalene-derived amino acid ester, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules with high stereochemical control, essential for developing active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in medicinal chemistry and catalyst development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides requiring specific stereochemistry for bioactivity.
• Catalyst & Ligand Synthesis: Acts as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Employed in the design and synthesis of peptide analogs and conformationally constrained amino acid derivatives.
• Material Science: A building block for specialty polymers and functional organic materials with tailored optical or electronic properties.
• Academic & R&D: Serves as a valuable reagent in university and corporate research laboratories for methodological development in organic chemistry.

Basic Information

Product Name	Methyl 2-Amino-3-(Naphthalen-1-Yl)Propanoate
CAS No.	136375-70-7
Molecular Formula	C₁₄H₁₅NO₂
Molecular Weight	229.27 g/mol
Synonyms	Methyl 2-Amino-3-(1-naphthyl)propanoate; 1-Naphthalenepropanoic acid, α-amino-, methyl ester; (S)-Methyl 2-amino-3-(naphthalen-1-yl)propanoate (if chiral); Methyl 3-(1-naphthyl)-2-aminopropionate; 2-Amino-3-(1-naphthyl)propionic acid methyl ester; α-Amino-β-(1-naphthyl)propionic acid methyl ester; 136375-70-7; L-1-Naphthylalanine methyl ester (common name).
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Amino-3-(Naphthalen-1-Yl)Propanoate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to meet the exacting standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (if applicable)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.