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D-Glucopyranose, 2-Azido-2-Deoxy-3,4-Bis-o-(Phenylmethyl)-, 1,6-Diacetate CAS NO 136172-58-2
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CAS No.:136172-58-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
D-Glucopyranose, 2-Azido-2-Deoxy-3,4-Bis-o-(Phenylmethyl)-, 1,6-Diacetate is a key synthetic intermediate in carbohydrate and medicinal chemistry, distinguished by its strategically protected and functionalized sugar backbone. This compound is essential for researchers and manufacturers developing novel pharmaceuticals, particularly as a versatile building block for glycosylation reactions and the synthesis of complex bioactive molecules. Its primary value lies in enabling the controlled synthesis of azido-sugar derivatives, which are critical for click chemistry applications and the development of antiviral agents, antibiotics, and glycoconjugate vaccines. Industries including pharmaceutical R&D, biotechnology, and fine chemical synthesis rely on this high-purity intermediate for advanced drug discovery and process development.
Application
- Pharmaceutical Intermediate: A crucial building block for the synthesis of nucleoside analogs and other antiviral or antibacterial agents.
- Glycobiology Research: Used in the study of carbohydrate-protein interactions and the synthesis of complex oligosaccharides.
- Click Chemistry Substrate: The azido group enables efficient Huisgen 1,3-dipolar cycloaddition reactions for bioconjugation and probe labeling.
- Glycoconjugate Vaccine Development: Serves as a precursor for antigenic carbohydrate moieties in vaccine candidates.
- Enzyme Inhibitor Synthesis: Used to create glycosidase inhibitors for therapeutic and research applications.
- Fine Chemical Synthesis: An intermediate in the multi-step synthesis of specialty chemicals and chiral auxiliaries.
Basic Information
| Product Name | D-Glucopyranose, 2-Azido-2-Deoxy-3,4-Bis-o-(Phenylmethyl)-, 1,6-Diacetate |
| CAS No. | 136172-58-2 |
| Molecular Formula | C24H27N3O7 |
| Molecular Weight | 469.49 g/mol |
| Synonyms | 1,6-Di-O-acetyl-2-azido-3,4-di-O-benzyl-2-deoxy-D-glucopyranose; 2-Azido-3,4-di-O-benzyl-2-deoxy-D-glucopyranose 1,6-diacetate; 2-Azido-2-deoxy-3,4-di-O-benzyl-D-glucopyranose 1,6-diacetate; 3,4-Di-O-benzyl-2-azido-2-deoxy-D-glucopyranose 1,6-diacetate; Benzyl-protected azido glucose diacetate; Azido-D-glucose derivative, benzylated and acetylated |
| EINECS | Contact for details |
Quality Control
Our D-Glucopyranose, 2-Azido-2-Deoxy-3,4-Bis-o-(Phenylmethyl)-, 1,6-Diacetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS). We provide full traceability and documentation, with Certificates of Analysis (COA) available for every shipment to support your regulatory and quality assurance requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in the original packaging away from direct light and moisture sources. For long-term storage, consider using desiccants and storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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