Description

2,6-Diazaspiro[3.4]Octane CAS NO 136098-13-0 is a high-value, nitrogen-containing spirocyclic building block of significant interest in modern organic synthesis. Its unique constrained bicyclic structure makes it a critical scaffold for medicinal chemistry, enabling the exploration of novel three-dimensional chemical space. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the design and synthesis of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a privileged scaffold in drug discovery for central nervous system (CNS) targets, oncology, and metabolic diseases.
• Medicinal Chemistry Building Block: Used to introduce conformational restraint and improve the pharmacokinetic properties (e.g., solubility, metabolic stability) of lead compounds.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and insecticides that require specific spatial orientation for target binding.
• Chemical Biology Probe Development: Utilized to create tool compounds for studying enzyme function and protein-protein interactions.
• Ligand Synthesis for Catalysis: Acts as a precursor for chiral ligands used in asymmetric synthesis and transition metal catalysis.
• Academic & Contract Research: A key reagent for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2,6-Diazaspiro[3.4]Octane
CAS No.	136098-13-0
Molecular Formula	C6H12N2
Molecular Weight	112.17 g/mol
Synonyms	2,6-Diazaspiro[3.4]octane; 1,4-Diazaspiro[2.3]hexane (incorrect numbering but common in early literature); Spiro[cyclopropane-1,2'-piperazine]; 2,6-Diaza-spiro[3.4]octane; 1-Azaspiro[2.3]hexan-4-amine (tautomeric form); Hexahydro-2,6-ethanopyrazine; 2,6-Diazaspiro-3.4-octane
EINECS	Contact for details

Quality Control

Our 2,6-Diazaspiro[3.4]Octane is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive R&D applications. We provide comprehensive analytical data including HPLC purity, NMR and MS confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is supplied with each batch, and custom synthesis to meet specific purity or packaging requirements is available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Optimal storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.