Description

Spiro[Chromene-2,4'-Piperidin]-4(3H)-One CAS NO 136081-84-0 is a complex spirocyclic organic compound featuring a fused chromene and piperidine ring system. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile scaffold in medicinal chemistry research. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential central nervous system (CNS) and other bioactive molecules.
• Medicinal Chemistry Research: Core scaffold for constructing compound libraries in drug discovery programs targeting various receptors.
• Organic Synthesis: Used in the development of complex heterocyclic compounds for academic and industrial research.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.
• Preclinical Studies: Utilized in the early-stage development of new chemical entities (NCEs) for pharmacological evaluation.

Basic Information

Product Name	Spiro[Chromene-2,4'-Piperidin]-4(3H)-One
CAS No.	136081-84-0
Molecular Formula	C₁₃H₁₅NO₂
Molecular Weight	217.26 g/mol
Synonyms	4H-Spiro[chromene-2,4'-piperidin]-4-one; 4H-Spiro[chromene-2,4'-piperidine]-4-one; 4-Oxospiro[chromene-2,4'-piperidine]; Spiro[chromene-2,4'-piperidin]-4-one; 136081-84-0; Spiro(chromene-2,4'-piperidin)-4(3H)-one; 4H-Spiro[1-benzopyran-2,4'-piperidin]-4-one
EINECS	Contact for details

Quality Control

Our production of Spiro[Chromene-2,4'-Piperidin]-4(3H)-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.