Description

6-Trifluoromethoxy-Pyridin-3-Ylamine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethoxy-substituted pyridine structure makes it an essential intermediate for creating compounds with enhanced biological activity and metabolic stability. This specialty chemical is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and kinase inhibitors.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Used in the creation of fluorinated liquid crystals, organic semiconductors, and advanced polymers.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes and enzyme inhibitors in drug discovery.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of tailored compounds for client-specific R&D projects.

Basic Information

Product Name	6-Trifluoromethoxy-Pyridin-3-Ylamine
CAS No.	135900-33-3
Molecular Formula	C7H5F3N2O
Molecular Weight	178.12 g/mol
Synonyms	3-Amino-6-(trifluoromethoxy)pyridine; 6-(Trifluoromethoxy)pyridin-3-amine; 5-Amino-2-(trifluoromethoxy)pyridine; 2-(Trifluoromethoxy)-5-aminopyridine; 6-Trifluoromethoxy-3-aminopyridine; 6-Trifluoromethoxypyridin-3-amine; 3-Pyridinamine, 6-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethoxy-Pyridin-3-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.