Description

Diethyl 2-Allyl-2-(tert-Butoxycarbonylamino)Malonate is a versatile and high-purity protected amino acid derivative, specifically a Boc-protected malonate ester. This compound is a critical building block in advanced organic synthesis, enabling the controlled introduction of functionalized amino acid motifs. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and peptidomimetics.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing non-natural amino acids and peptide analogs used in drug discovery and development.
• Peptidomimetic Synthesis: Essential for constructing peptide-like chains with enhanced metabolic stability and bioavailability for therapeutic applications.
• API Manufacturing: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs), particularly those targeting neurological and metabolic disorders.
• Asymmetric Synthesis: Serves as a chiral precursor or auxiliary in stereoselective reactions to create enantiomerically pure compounds.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and labeled compounds for studying biological pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized fine chemicals for clients.

Basic Information

Product Name	Diethyl 2-Allyl-2-(tert-Butoxycarbonylamino)Malonate
CAS No.	135722-55-3
Molecular Formula	C16H27NO6
Molecular Weight	329.39 g/mol
Synonyms	Diethyl (N-Boc-2-amino-2-allyl)malonate; Diethyl 2-(N-tert-Butoxycarbonylamino)-2-allylmalonate; 2-Allyl-2-[(tert-butoxycarbonyl)amino]propanedioic acid diethyl ester; Boc-2-amino-2-allylmalonic acid diethyl ester; (N-Boc-2-amino-2-allyl)malonic Acid Diethyl Ester; 2-Allylmalonic acid diethyl ester N-Boc derivative; Diethyl 2-allyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanedioate
EINECS	Contact for details

Quality Control

Our Diethyl 2-Allyl-2-(tert-Butoxycarbonylamino)Malonate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.