Description

2-Bromo-3-Benzyloxy-4-Methoxybenzoic Acid Methyl Ester is a high-purity synthetic intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a versatile building block in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active compounds and materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new active ingredients for crop protection and herbicides.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of advanced polymers and liquid crystals.
• Academic & Institutional R&D: Utilized in university and government laboratories for fundamental organic chemistry research and methodology development.
• Custom Synthesis & Contract Manufacturing: A critical component for companies offering bespoke chemical synthesis services to the life sciences sector.

Basic Information

Product Name	2-Bromo-3-Benzyloxy-4-Methoxybenzoic Acid Methyl Ester
CAS No.	135586-19-5
Molecular Formula	C16H15BrO4
Molecular Weight	351.19 g/mol
Synonyms	Methyl 2-Bromo-3-Benzyloxy-4-Methoxybenzoate; Benzoic acid, 2-bromo-3-(phenylmethoxy)-4-methoxy-, methyl ester; 2-Bromo-3-benzyloxy-4-methoxy methyl benzoate; Methyl 2-bromo-3-(benzyloxy)-4-methoxybenzoate; 135586-19-5; Methyl ester of 2-bromo-3-benzyloxy-4-methoxybenzoic acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Benzyloxy-4-Methoxybenzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full batch traceability are provided and available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.