Description

Lobaplatin CAS NO 135558-11-1 is a third-generation platinum-based antineoplastic agent, a potent chemotherapeutic compound designed for targeted cancer treatment. Its primary value lies in its distinct chemical structure, which aims to reduce toxicity and overcome resistance mechanisms associated with earlier platinum drugs. This product is essential for pharmaceutical R&D, advanced oncology research, and the synthesis of novel therapeutic formulations. It serves as a critical raw material for manufacturers developing next-generation chemotherapeutic agents.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active component in injectable chemotherapeutic formulations for treating various cancers.
• Oncology Research: A key reference standard and investigational compound in preclinical and clinical studies for evaluating new cancer therapies.
• Drug Development: Used in the synthesis and development of novel platinum-based drug candidates and combination therapies.
• Biochemical Studies: Employed in mechanistic studies to understand DNA binding, cell cycle arrest, and apoptosis induction in cancer cells.
• GMP Manufacturing: Sourced as a high-purity intermediate for the commercial-scale production of finished dosage forms under Good Manufacturing Practice (GMP) guidelines.

Basic Information

Product Name	Lobaplatin
CAS No.	135558-11-1
Molecular Formula	C9H18N2O3Pt
Molecular Weight	437.34 g/mol
Synonyms	1,2-Diaminomethylcyclobutaneplatinum(II) lactate; D-19466; Lobaplatinum; (1R,2R)-1,2-Bis(aminomethyl)cyclobutaneplatinum(II) Lactate; Lobaplatin (USAN); Lobaplatina; Lobaplatine
EINECS	Contact for details

Quality Control

Our Lobaplatin is manufactured and tested to meet stringent pharmaceutical-grade standards. Quality is assured through a comprehensive battery of analytical tests including HPLC for purity and assay, residual solvent analysis (GC), and heavy metal testing. We provide full traceability and support regulatory filings. A detailed Certificate of Analysis (COA), confirming identity, purity, and compliance with agreed specifications, is supplied with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere conditions to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.