Description

3H-Indolium, 2-[7-(1,3-Dihydro-1,3,3-Trimethyl-5-Sulfo-2H-Indol-2-Ylidene)-1,3,5-Heptatrienyl]-1,3,3-Trimethyl-5-Sulfo-, Inner Salt, Sodium Salt, Monohydrate is a high-purity, water-soluble cyanine dye derivative, recognized for its excellent photostability and strong near-infrared (NIR) absorption. This compound matters as a critical functional material, offering precise optical properties essential for advanced diagnostic and imaging technologies. It is primarily needed by manufacturers in the biotechnology, medical diagnostics, and analytical chemistry sectors for applications requiring sensitive light detection.

Application

• Fluorescent Labeling Agent: Used as a covalent tag for biomolecules (proteins, nucleic acids) in fluorescence microscopy and bioassays.
• Optical Imaging Probes: A key component in the formulation of contrast agents for in vivo and in vitro near-infrared fluorescence imaging.
• Laser Dye Medium: Employed in the production of tunable dye lasers for scientific and medical laser systems.
• Photodynamic Therapy (PDT) Research: Investigated as a potential photosensitizer in therapeutic applications for targeted cell ablation.
• Sensor Fabrication: Integrated into chemical and biological sensors for the detection of specific analytes based on fluorescence quenching or enhancement.
• Non-linear Optical Materials: Used in research and development of materials for photonics and optoelectronic devices.

Basic Information

Product Name	3H-Indolium, 2-[7-(1,3-Dihydro-1,3,3-Trimethyl-5-Sulfo-2H-Indol-2-Ylidene)-1,3,5-Heptatrienyl]-1,3,3-Trimethyl-5-Sulfo-, Inner Salt, Sodium Salt, Monohydrate
CAS No.	135408-43-4
Molecular Formula	C29H33N2O7S2Na · H2O
Molecular Weight	614.70 g/mol (Monohydrate)
Synonyms	IR-783; IR 783; IR783; 1H-Benz[e]indolium, 2-[7-(1,3-dihydro-1,3,3-trimethyl-5-sulfo-2H-benz[e]indol-2-ylidene)-1,3,5-heptatrienyl]-1,3,3-trimethyl-5-sulfo-, inner salt, sodium salt, monohydrate; 2-[7-(1,3-Dihydro-1,3,3-trimethyl-5-sulfo-2H-indol-2-ylidene)-1,3,5-heptatrienyl]-1,3,3-trimethyl-5-sulfo-3H-indolium inner salt sodium salt monohydrate; Cyanine dye IR-783; NIR dye IR-783; Heptamethine cyanine dye IR-783
EINECS	Contact for details

Quality Control

Our 3H-Indolium dye is produced under strict quality management systems to ensure batch-to-batch consistency and high performance. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectrophotometry for absorbance/emission verification, and elemental analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Dark green to blue-black powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Absorption Maximum (λmax)	783 nm ± 5 nm (in methanol)
Emission Maximum	~805 nm ± 10 nm (in methanol)
Extinction Coefficient (ε)	≥ 200,000 L·mol⁻¹·cm⁻¹
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.