Description

1,2-Pyrrolidinedicarboxylic Acid, 1-(1,1-Dimethylethyl) 2-Ethyl Ester, (2S)- is a high-purity, chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for constructing complex molecules with defined stereochemistry, which is critical for efficacy in many applications. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the research and production of enantiomerically pure drugs, particularly those targeting the central nervous system or requiring specific biological activity.
• Agrochemical Synthesis: Used in the development of novel, stereoselective pesticides and herbicides where the specific spatial orientation of the molecule affects its biological target.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalytic reactions to create other chiral compounds.
• Peptidomimetics Research: Employed in medicinal chemistry for designing and synthesizing peptide analogs that mimic natural peptides but with improved stability or bioavailability.
• Fine Chemical Production: Acts as a building block for various specialty and fine chemicals requiring a defined pyrrolidine backbone with protected carboxylic acid groups.

Basic Information

Product Name	1,2-Pyrrolidinedicarboxylic Acid, 1-(1,1-Dimethylethyl) 2-Ethyl Ester, (2S)-
CAS No.	135097-23-3
Molecular Formula	C13H23NO4
Molecular Weight	257.33 g/mol
Synonyms	(2S)-1-(tert-Butyl) 2-ethyl pyrrolidine-1,2-dicarboxylate; L-Proline, 1-(1,1-dimethylethyl) 2-ethyl ester; tert-Butyl (S)-2-(ethoxycarbonyl)pyrrolidine-1-carboxylate; (S)-1-Boc-2-ethoxycarbonylpyrrolidine; Boc-L-Proline ethyl ester; (S)-1-(tert-Butoxycarbonyl)-2-(ethoxycarbonyl)pyrrolidine; Ethyl (S)-1-Boc-pyrrolidine-2-carboxylate; (S)-1-Boc-pyrrolidine-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 1,2-Pyrrolidinedicarboxylic Acid, 1-(1,1-Dimethylethyl) 2-Ethyl Ester, (2S)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.