Description

Cyclobutanecarboxylic Acid, 2-Methyl-, Methyl Ester, (1R,2S)- (9Ci) is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. This compound matters because its unique cyclobutane scaffold and defined stereochemistry enable the construction of complex molecules with precise three-dimensional architecture. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly those requiring constrained ring systems.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the cyclobutane ring can impart specific biological activity and stability.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new stereoselective catalytic reactions.
• Material Science Precursor: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Fragrance and Flavor Chemistry: Acts as an intermediate for synthesizing complex odorants and flavor compounds with specific stereochemical notes.
• Academic and R&D Laboratories: A critical reagent for methodological studies in organic chemistry and for exploring new chemical spaces in drug discovery programs.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 2-Methyl-, Methyl Ester, (1R,2S)- (9Ci)
CAS No.	134877-07-9
Molecular Formula	C7H12O2
Molecular Weight	128.17 g/mol
Synonyms	(1R,2S)-2-Methylcyclobutanecarboxylic acid methyl ester; Methyl (1R,2S)-2-methylcyclobutanecarboxylate; (1R,2S)-Methyl 2-methylcyclobutanecarboxylate; (-)-(1R,2S)-Methyl 2-methylcyclobutanecarboxylate; trans-(-)-Methyl 2-methylcyclobutanecarboxylate; Chiral methyl 2-methylcyclobutanecarboxylate; Cyclobutanecarboxylic acid, 2-methyl-, methyl ester, (1R,2S)-
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 2-Methyl-, Methyl Ester, (1R,2S)- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high chiral purity. Each lot undergoes comprehensive analytical characterization, including chiral HPLC for enantiomeric excess (ee) verification, to meet the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.