Description

21-Fluoro-16-Methyl-19-Norprogesterone is a high-purity synthetic steroid derivative, specifically a fluorinated and methylated analog of 19-norprogesterone. This compound is valued for its enhanced metabolic stability and specific receptor binding profile compared to its parent structure, making it a critical intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in the fields of endocrinology and oncology.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe compound in studies of steroid hormone receptors and their signaling pathways.
• Drug Discovery: Serves as a core scaffold for medicinal chemistry programs aimed at developing new therapeutic agents with modified activity and pharmacokinetics.
• Metabolic Studies: Employed to investigate the impact of fluorination and methylation on the metabolic fate and biological half-life of steroid molecules.

Basic Information

Product Name	21-Fluoro-16-Methyl-19-Norprogesterone
CAS No.	134785-66-3
Molecular Formula	C₂₁H₂₉FO₂
Molecular Weight	332.46 g/mol
Synonyms	21-Fluoro-16α-methyl-19-norpregn-4-ene-3,20-dione; 16α-Methyl-21-fluoro-19-norprogesterone; 21-Fluoro-16-methyl-19-norpregn-4-ene-3,20-dione; 16-Methyl-21-fluoro-19-norprogesterone; 19-Nor-21-fluoro-16-methylprogesterone
EINECS	Contact for details

Quality Control

Our 21-Fluoro-16-Methyl-19-Norprogesterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.