Description

Bromoacetylphosphonate CAS NO 134780-94-2 is a specialized organophosphorus compound featuring a reactive bromoacetyl group. This unique bifunctional structure makes it a valuable chemical building block for synthesizing complex molecules, particularly in advanced research and development. It is primarily utilized by pharmaceutical researchers and agrochemical chemists for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Synthesis: Building block for developing new herbicides, insecticides, and plant growth regulators with specific modes of action.
• Chemical Biology Probe: Used to create affinity labels or activity-based probes for studying enzyme function and mechanism.
• Peptide Mimetic Research: Employed in the design and synthesis of phosphonate-based peptide analogs and transition-state analogs.
• Material Science: Intermediate for synthesizing functionalized polymers or surface-modifying agents with specific reactive handles.
• Cross-coupling Reactions: Serves as an electrophilic partner in various metal-catalyzed cross-coupling reactions to form carbon-carbon bonds.

Basic Information

Product Name	Bromoacetylphosphonate
CAS No.	134780-94-2
Molecular Formula	C4H6BrO4P
Molecular Weight	228.97 g/mol
Synonyms	Bromoacetylphosphonic Acid; (Bromoacetyl)phosphonic Acid; Phosphono(bromoacetic) Acid; Bromoacetylphosphonic Acid Diethyl Ester (common ester form); 2-Bromo-2-oxoethylphosphonic Acid; NSC 339586; Bromoacetylphosphonate Ester
EINECS	Contact for details

Quality Control

Our Bromoacetylphosphonate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets precise research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.