Description

L-Proline, Propyl Ester (9Ci) is a protected derivative of the amino acid L-proline, where the carboxylic acid group is esterified with propanol. This modification enhances its lipophilicity and stability, making it a valuable chiral building block and intermediate in sophisticated organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide-based drugs, enzyme inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry is required for activity.
• Peptide Chemistry: Serves as a protected proline residue in solid-phase and solution-phase peptide synthesis (SPPS) to prevent side reactions.
• Asymmetric Catalysis: Employed as a precursor for ligands or organocatalysts used in stereoselective chemical transformations.
• Biochemical Research: Utilized as a standard or reagent in metabolic studies and proteomics research.
• Fine Chemical Production: Acts as a building block for the synthesis of complex natural products, flavors, and fragrances.

Basic Information

Product Name	L-Proline, Propyl Ester (9Ci)
CAS No.	134666-85-6
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	L-Proline propyl ester; (S)-Proline propyl ester; Propyl L-prolinate; 1-Propyl (2S)-pyrrolidine-2-carboxylate; Propan-1-yl (2S)-pyrrolidine-2-carboxylate; L-Pyrrolidine-2-carboxylic acid propyl ester; (S)-(-)-Proline propyl ester; L-Proline n-propyl ester
EINECS	Contact for details

Quality Control

Our L-Proline, Propyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing specific results for identity, assay, and purity is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.