Description

2-Pyridineethanol,α-Ethynyl-(9Ci) is a specialized heterocyclic building block featuring both pyridine and ethynyl alcohol functionalities. This compound is valued for its unique molecular architecture, which makes it a versatile intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and novel ligands.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including cross-coupling and click chemistry reactions.
• Material Science Research: Investigated as a monomer or functional additive for developing novel polymers with specific electronic or optical properties.

Basic Information

Product Name	2-Pyridineethanol,α-Ethynyl-(9Ci)
CAS No.	134541-95-0
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	2-(1-Ethynyl-2-hydroxyethyl)pyridine; α-Ethynyl-2-pyridineethanol; 1-(2-Pyridinyl)-3-butyn-1-ol; 3-Butyn-1-ol, 1-(2-pyridinyl)-; 2-(1-Ethynyl-2-hydroxyethyl)pyridine; (2-Pyridyl)ethynylmethanol (derivative); 1-(Pyridin-2-yl)-3-butyn-1-ol
EINECS	Contact for details

Quality Control

Our 2-Pyridineethanol,α-Ethynyl-(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports production for research and cGMP-grade applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.