Description

Azetidine-2-Carboxylic Acid Methyl Ester is a high-value, heterocyclic building block and chiral synthon of significant interest in advanced organic synthesis. Its constrained four-membered azetidine ring and ester functionality make it a critical precursor for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, including protease inhibitors, β-lactam analogs, and other bioactive molecules with constrained ring systems.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that incorporate the azetidine moiety for enhanced activity.
• Peptidomimetics & Bioactive Compound Research: Serves as a proline analog or a constrained scaffold in designing peptidomimetics to improve metabolic stability and binding affinity.
• Organocatalyst & Ligand Precursor: Employed in the development of novel chiral catalysts and ligands for asymmetric synthesis.
• Material Science Research: Investigated as a monomer or functional modifier for creating polymers with unique properties.
• Chemical Biology Probes: Utilized in the synthesis of probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Azetidine-2-Carboxylic Acid Methyl Ester
CAS No.	134419-57-1
Molecular Formula	C5H9NO2
Molecular Weight	115.13 g/mol
Synonyms	Methyl Azetidine-2-carboxylate; Methyl 2-Azetidinecarboxylate; (S)-Azetidine-2-carboxylic acid methyl ester; L-Azetidine-2-carboxylic acid methyl ester; Azetidine-2-carboxylic acid methyl ester; 2-Azetidinecarboxylic acid, methyl ester; Methyl (S)-azetidine-2-carboxylate; Methyl L-azetidine-2-carboxylate
EINECS	Contact for details

Quality Control

Our Azetidine-2-Carboxylic Acid Methyl Ester is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Due to its sensitivity to strong bases and organic solvents as indicated, it should be kept separate from incompatible materials. For long-term storage, maintaining the container under an inert atmosphere (e.g., nitrogen or argon) is recommended to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.