Description

5-Bromo-2-(3-Methyl-3-Hydroxy-1-Butynyl)Pyridine is a high-value pyridine derivative and a versatile chemical building block. This compound is critical for advanced organic synthesis, particularly in the development of complex pharmaceutical intermediates and active ingredients. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a sophisticated building block for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for advanced materials, such as organic semiconductors or liquid crystals.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tools to study biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up campaigns in fine chemical production.

Basic Information

Product Name	5-Bromo-2-(3-Methyl-3-Hydroxy-1-Butynyl)Pyridine
CAS No.	134321-95-2
Molecular Formula	C11H10BrNO
Molecular Weight	252.11 g/mol
Synonyms	5-Bromo-2-(3-methyl-3-hydroxybut-1-yn-1-yl)pyridine; 2-(5-Bromo-2-pyridinyl)-3-methyl-3-butyn-2-ol; 3-Methyl-1-(5-bromo-2-pyridinyl)-2-propyn-1-ol; 5-Bromo-2-(1-hydroxy-1-methyl-2-propynyl)pyridine; 5-Bromo-2-(3-hydroxy-3-methyl-1-butynyl)pyridine; 134321-95-2; 5-Bromo-2-(3-methyl-3-hydroxybut-1-ynyl)pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(3-Methyl-3-Hydroxy-1-Butynyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider the use of desiccants or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.