Description

5-Hydroxy-6-(N,n-Bis(2-Chloroethyl)Aminomethyl)Naphthalene-1,8-Carbolactone is a specialized naphthalene-based lactone derivative with a functionalized nitrogen mustard side chain, making it a compound of significant interest in advanced chemical synthesis. Its core value lies in its potential as a key synthetic intermediate or a precursor for developing targeted bioactive molecules. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those working on novel drug discovery programs or advanced crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential anticancer agents or other therapeutic compounds leveraging the nitrogen mustard pharmacophore.
• Agrochemical Research: Used in the development of novel herbicides or pesticides, where its complex structure can contribute to new modes of action.
• Chemical Biology Probe: Acts as a tool compound for studying biological pathways involving alkylation or for targeted protein degradation research (e.g., PROTACs).
• Advanced Material Synthesis: Potential precursor for functionalized organic materials or ligands used in catalysis and material science.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	5-Hydroxy-6-(N,n-Bis(2-Chloroethyl)Aminomethyl)Naphthalene-1,8-Carbolactone
CAS No.	134274-45-6
Molecular Formula	C18H19Cl2NO3
Molecular Weight	368.26 g/mol
Synonyms	5-Hydroxy-6-[[bis(2-chloroethyl)amino]methyl]-1,8-naphthalic anhydride; 6-[[Bis(2-chloroethyl)amino]methyl]-5-hydroxy-1H,3H-naphtho[1,8-cd]pyran-1,3-dione; 5-Hydroxy-6-(bis(2-chloroethyl)aminomethyl)-1,8-naphthalic anhydride; N,N-Bis(2-chloroethyl)-5-hydroxy-1,8-naphthalimide-6-methylamine; 134274-45-6; 5-Hydroxy-6-(N,N-bis(2-chloroethyl)aminomethyl)-1,8-naphthalic anhydride
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-6-(N,n-Bis(2-Chloroethyl)Aminomethyl)Naphthalene-1,8-Carbolactone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identification, and impurity profiles is provided with every shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.