Description

6-o-Benzoyl-3-o-Benzyl-1,2-o-Isopropylidene-5-o-Methanesulfonyl-α-D-Glucofuranose is a sophisticated, multi-protected carbohydrate derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in its precisely positioned protecting groups, which allow for selective deprotection and further functionalization, enabling the controlled construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of nucleoside analogs, antiviral agents, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Antiviral Drug Development: Used in the research and production of active pharmaceutical ingredients (APIs) targeting viruses such as HIV, hepatitis, and herpes.
• Carbohydrate Chemistry Research: A versatile starting material for studying glycosylation reactions and synthesizing complex oligosaccharides or glycoconjugates.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, chiral ligands, and catalysts requiring high stereochemical control.
• Process Chemistry & Scale-Up: Suitable for process development and optimization from laboratory-scale research to pilot and commercial manufacturing.
• Academic & Industrial R&D: A valuable tool for chemists in universities and corporate R&D labs exploring new synthetic methodologies and bioactive molecules.

Basic Information

Product Name	6-o-Benzoyl-3-o-Benzyl-1,2-o-Isopropylidene-5-o-Methanesulfonyl-α-D-Glucofuranose
CAS No.	134198-40-6
Molecular Formula	C25H28O8S
Molecular Weight	488.55 g/mol
Synonyms	5-O-Methanesulfonyl-1,2-O-isopropylidene-3-O-benzyl-6-O-benzoyl-α-D-glucofuranose; 1,2-O-Isopropylidene-3-O-benzyl-6-O-benzoyl-5-O-methanesulfonyl-α-D-glucofuranose; 5-O-Mesyl-1,2:5,6-di-O-isopropylidene-3-O-benzyl-α-D-allofuranose (related intermediate); 3-O-Benzyl-1,2-O-isopropylidene-6-O-benzoyl-5-O-methanesulfonyl-α-D-glucofuranose; 5-O-Mesyl-3-O-Bn-6-O-Bz-1,2-O-isopropylidene-α-D-glucofuranose; Protected D-Glucofuranose Methanesulfonate; α-D-Glucofuranose, 6-benzoyl-3-benzyl-1,2-isopropylidene 5-methanesulfonate
EINECS	Contact for details

Quality Control

Our production of 6-o-Benzoyl-3-o-Benzyl-1,2-o-Isopropylidene-5-o-Methanesulfonyl-α-D-Glucofuranose adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR (1H & 13C), and Mass Spectrometry to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.