Description

Cyclobutanecarboxylic Acid, 3-Ethylidene-2-Methyl-, Methyl Ester, [1S- is a high-purity, stereochemically defined organic building block of significant interest in advanced chemical synthesis. This compound matters because its unique cyclobutane core and functionalized ester group make it a valuable chiral intermediate for constructing complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates with complex cyclic structures.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the cyclobutane ring system can impart unique biological activity and stability.
• Material Science Research: Acts as a monomer or precursor for synthesizing specialty polymers with tailored thermal and mechanical properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for cycloaddition reactions, ring-opening transformations, and the synthesis of natural product analogs.
• Flavor & Fragrance Chemistry: Potential use in the synthesis of novel aroma chemicals and flavoring agents due to its complex, constrained carbon skeleton.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 3-Ethylidene-2-Methyl-, Methyl Ester, [1S-
CAS No.	134175-98-7
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	(1S)-3-Ethylidene-2-methylcyclobutanecarboxylic acid methyl ester; Methyl (1S)-3-ethylidene-2-methylcyclobutanecarboxylate; [1S-(3E)]-3-Ethylidene-2-methylcyclobutanecarboxylic Acid Methyl Ester; (1S,2S)-3-Ethylidene-2-methylcyclobutanecarboxylic acid methyl ester; (S)-Methyl 3-ethylidene-2-methylcyclobutanecarboxylate; Cyclobutanecarboxylic acid, 3-ethylidene-2-methyl-, methyl ester, (1S)-; 134175-98-7
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 3-Ethylidene-2-Methyl-, Methyl Ester, [1S- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.