Description

2-Iodo-5'-Azido-Delta(8)-Tetrahydrocannabinol CAS NO 134141-74-5 is a synthetic cannabinoid derivative, specifically a functionalized analog of δ-8-THC. This compound is of significant interest as a key intermediate and research chemical for the development of novel cannabinoid-based pharmaceuticals and biochemical probes. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and specialized chemical synthesis facilities engaged in cannabinoid science and medicinal chemistry.

Application

• Pharmaceutical Research & Development: Serves as a crucial synthetic intermediate in the creation of novel cannabinoid receptor ligands and potential therapeutic agents.
• Biochemical Probe Synthesis: Used to develop photoaffinity labeling agents and other molecular probes for studying cannabinoid receptor (CB1/CB2) structure, function, and signaling pathways.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies to explore the impact of halogen and azide substitutions on cannabinoid activity.
• Reference Standard: Acts as a high-purity analytical standard for method development and quality control in cannabinoid analysis.
• Precursor for Click Chemistry: The azide functional group enables its use in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and library synthesis.

Basic Information

Product Name	2-Iodo-5'-Azido-Delta(8)-Tetrahydrocannabinol
CAS No.	134141-74-5
Molecular Formula	C21H27IN3O2
Molecular Weight	504.37 g/mol
Synonyms	2-Iodo-5'-azido-δ8-THC; 5'-Azido-2-iodo-δ8-tetrahydrocannabinol; δ8-THC-2-iodo-5'-azide; 2-Iodo-5'-azidocannabinol; (6aR,10aR)-9-(Hydroxymethyl)-6,6-dimethyl-3-(2-iodo-5-azidopentyl)-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
EINECS	Contact for details

Quality Control

Our 2-Iodo-5'-Azido-Delta(8)-Tetrahydrocannabinol is manufactured under strict quality protocols. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing results from NMR (1H, 13C), HPLC, and mass spectrometry are provided. We adhere to cGMP principles for research chemicals to guarantee reliable and reproducible performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is light-sensitive (store away from light). Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.