Description

4-[(Triisopropylsilyl)oxy]propiophenone is a specialized organosilicon-protected ketone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the triisopropylsilyl (TIPS) protecting group, which provides exceptional steric bulk and stability for selective reactions, enabling the construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise control over synthetic pathways is paramount.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for protecting hydroxyl groups during complex transformations.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where its protecting group strategy aids in creating specific bioactive structures.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex natural products, fragrances, and specialty chemicals via controlled carbonyl chemistry.
• Material Science Precursor: Acts as a starting material for synthesizing functionalized organic molecules that can be incorporated into polymers or advanced organic electronic materials.
• Process Chemistry: Valued in scale-up and optimization of synthetic routes due to the robustness and ease of removal of the TIPS protecting group under mild conditions.

Basic Information

Product Name	4-[(Triisopropylsilyl)oxy]propiophenone
CAS No.	134136-88-2
Molecular Formula	C19H32O2Si
Molecular Weight	320.55 g/mol
Synonyms	1-[4-[(Triisopropylsilyl)oxy]phenyl]-1-propanone; 4-(Triisopropylsiloxy)propiophenone; p-(Triisopropylsilyloxy)propiophenone; Propiophenone, 4-[(triisopropylsilyl)oxy]-; TIPS-protected 4-hydroxypropiophenone; 4-Hydroxypropiophenone TIPS ether; 4-TIPSoxypropiophenone
EINECS	Contact for details

Quality Control

Our 4-[(Triisopropylsilyl)oxy]propiophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and industrial use. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. Certificates of Analysis (COA) detailing specific results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.