Description

3-(T-Butyldimethylsiloxy)Iodobenzene is a high-value organosilicon-protected aryl iodide intermediate, essential for advanced organic synthesis. This compound is specifically engineered to provide superior stability and reactivity in demanding cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is a critical reagent for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring aryl-aryl bond formation via Suzuki, Stille, or other palladium-catalyzed cross-couplings.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the introduction of a substituted phenyl group is required.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its iodine moiety allows for further functionalization.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic pathways in organic chemistry laboratories worldwide.

Basic Information

Product Name	3-(T-Butyldimethylsiloxy)Iodobenzene
CAS No.	133910-12-0
Molecular Formula	C₁₂H₁₉IOSi
Molecular Weight	334.27 g/mol
Synonyms	3-[(tert-Butyldimethylsilyl)oxy]iodobenzene; 3-Iodophenyl tert-butyldimethylsilyl ether; 3-(Tert-Butyldimethylsiloxy)Iodobenzene; 3-Iodo-1-[(tert-butyldimethylsilyl)oxy]benzene; 3-TBDMS-O-C6H4-I; 3-Iodophenol TBDMS ether; 3-(tert-Butyl(dimethyl)silyl)oxy-1-iodobenzene
EINECS	Contact for details

Quality Control

Every batch of 3-(T-Butyldimethylsiloxy)Iodobenzene is manufactured and tested under strict quality management protocols to ensure consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to meet the rigorous standards demanded by GMP and ISO-guided environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.