Description

L-Ribono-1,4-Lactone is a high-purity chiral building block and sugar derivative of significant interest in advanced organic synthesis. This compound serves as a critical precursor for the development of nucleoside analogs, antiviral agents, and other biologically active molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require enantiomerically pure intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used in the study of carbohydrate metabolism and enzymatic processes.
• Fine Chemical Synthesis: Building block for complex natural products, flavors, and fragrances requiring specific stereochemistry.
• Glycochemistry: Valuable starting material for the preparation of glycosides and carbohydrate mimetics.
• Diagnostic Reagents: Potential use in the development of assay components and diagnostic markers.
• Cosmetic Actives: Intermediate for synthesizing sugar-based moisturizing agents or skin-conditioning ingredients.

Basic Information

Product Name	L-Ribono-1,4-Lactone
CAS No.	133908-85-7
Molecular Formula	C5H8O5
Molecular Weight	148.11 g/mol
Synonyms	L-Ribonic acid γ-lactone; (3R,4S,5R)-3,4,5-Trihydroxydihydrofuran-2(3H)-one; L(-)-Ribono-1,4-lactone; L-Ribonolactone; 1,4-L-Ribonolactone; L-Ribose acid lactone; L-Ribonic lactone
EINECS	Contact for details

Quality Control

Our L-Ribono-1,4-Lactone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.