Description

Methyl 3,3,3-Trimethoxypropionate is a versatile specialty ester and a key protected synthon in advanced organic synthesis. Its value lies in its unique structure, featuring three methoxy groups that can be selectively deprotected or transformed, making it an essential building block for complex molecule construction. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing active ingredients and novel materials.

Application

• Pharmaceutical Intermediates: A crucial protected synthon for the synthesis of complex drug molecules, particularly those requiring β-keto ester or malonate-type frameworks.
• Agrochemical Synthesis: Used as a building block in the production of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Manufacturing: Serves as a precursor for dyes, pigments, flavors, and fragrances requiring specific alkoxy-substituted propionate structures.
• Polymer & Material Science: Employed in the development of specialty polymers, coatings, and resins where its functional groups can be incorporated into the polymer backbone.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry, including studies on protecting group chemistry and new catalytic transformations.

Basic Information

Product Name	Methyl 3,3,3-Trimethoxypropionate
CAS No.	133871-52-0
Molecular Formula	C7H14O5
Molecular Weight	178.18 g/mol
Synonyms	Methyl 3,3,3-trimethoxypropanoate; 3,3,3-Trimethoxypropionic Acid Methyl Ester; Trimethyl Orthoacetate Acetic Acid Methyl Ester; Methyl β,β,β-trimethoxypropionate; Propanoic acid, 3,3,3-trimethoxy-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3,3,3-Trimethoxypropionate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.