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2-Azido-4,6-o-Benzylidene-n-(tert-Butoxycarbonyl)-1,2,5-Trideoxy-1,5-Imino-D-Glucitol CAS NO 133697-23-1


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CAS No.:133697-23-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Azido-4,6-o-Benzylidene-n-(tert-Butoxycarbonyl)-1,2,5-Trideoxy-1,5-Imino-D-Glucitol is a sophisticated, high-purity synthetic intermediate crucial for advanced organic and medicinal chemistry research. This compound is specifically engineered as a key building block for the synthesis of complex nitrogen-containing heterocycles and carbohydrate mimetics. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers developing novel therapeutics, particularly in the areas of glycosidase inhibitors and antiviral agents.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of novel iminosugar-based drug candidates targeting metabolic and viral diseases.
  • Glycosidase Inhibitor Research: Serves as a core scaffold for developing potent and selective inhibitors of carbohydrate-processing enzymes.
  • Carbohydrate Mimetic Synthesis: Used to create stable analogs of natural sugars for biochemical studies and probe development.
  • Antiviral Agent Development: Employed in the research and production of compounds that interfere with viral attachment and entry mechanisms.
  • Chemical Biology Tool: Acts as a versatile handle for click chemistry (via the azido group) to label or conjugate biomolecules.
  • Academic & Institutional Research: A valuable reagent for universities and research institutes exploring glycoscience and medicinal chemistry.

Basic Information

Product Name 2-Azido-4,6-o-Benzylidene-n-(tert-Butoxycarbonyl)-1,2,5-Trideoxy-1,5-Imino-D-Glucitol
CAS No. 133697-23-1
Molecular Formula C19H24N4O6
Molecular Weight 404.42 g/mol
Synonyms 1,5-Dideoxy-1,5-imino-2-azido-4,6-O-benzylidene-N-(tert-butoxycarbonyl)-D-glucitol; N-Boc-2-azido-4,6-O-benzylidene-1,2,5-trideoxy-1,5-imino-D-glucitol; 2-Azido-4,6-O-benzylidene-N-Boc-1,2,5-trideoxy-1,5-imino-D-glucitol; Boc-protected azido benzylidene iminosugar; CAS 133697-23-1; (3aR,5R,6S,6aR)-5-(Azidomethyl)-2,2-dimethyl-6-[(R)-phenylmethylene]tetrahydrofuro[2,3-d][1,3]dioxole-4a(6H)-carboxylic acid tert-butyl ester
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Quality Control

Our 2-Azido-4,6-o-Benzylidene-n-(tert-Butoxycarbonyl)-1,2,5-Trideoxy-1,5-Imino-D-Glucitol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. For long-term storage, consider keeping the material under an inert atmosphere (e.g., nitrogen or argon) to maintain stability. Keep away from heat and open flame.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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