Description

cis-Methyl 3-Methylpiperidine-4-Carboxylate Hcl CAS NO 133567-10-9 is a high-purity piperidine derivative, specifically the cis-isomer of methyl 3-methylpiperidine-4-carboxylate hydrochloride. This compound serves as a critical chiral building block and pharmaceutical intermediate in advanced organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the construction of complex molecules with specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the specific stereochemistry of the piperidine ring is crucial for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing novel heterocyclic compounds.
• Fine Chemical Production: Acts as a building block for specialty chemicals, flavors, and fragrances requiring high stereochemical purity.

Basic Information

Product Name	cis-Methyl 3-Methylpiperidine-4-Carboxylate Hcl
CAS No.	133567-10-9
Molecular Formula	C8H16ClNO2
Molecular Weight	193.67 g/mol
Synonyms	Methyl cis-3-methylpiperidine-4-carboxylate hydrochloride; (3R,4S)- and (3S,4R)-Methyl 3-methylpiperidine-4-carboxylate hydrochloride; 4-Piperidinecarboxylic acid, 3-methyl-, methyl ester, hydrochloride, cis-; Methyl 3-methyl-4-piperidinecarboxylate hydrochloride (cis); cis-3-Methyl-4-(methoxycarbonyl)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our cis-Methyl 3-Methylpiperidine-4-Carboxylate Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for isomeric purity and standard pharmacopeial identification tests, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isomeric Purity (Chiral HPLC)	≥ 99.0% cis-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.