Description

Benzoic Acid, 4-(Bromomethyl)-3-Chloro-, Ethyl Ester (CAS NO 133486-61-0) is a high-purity, multi-functional halogenated aromatic ester that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular structure, featuring both bromomethyl and chloro substituents, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where halogenated aromatic cores are required.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized as a starting material for synthesizing molecular probes and tags for studying biological systems and protein interactions.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	Benzoic Acid, 4-(Bromomethyl)-3-Chloro-, Ethyl Ester
CAS No.	133486-61-0
Molecular Formula	C10H10BrClO2
Molecular Weight	277.54 g/mol
Synonyms	Ethyl 4-(Bromomethyl)-3-chlorobenzoate; 3-Chloro-4-(bromomethyl)benzoic Acid Ethyl Ester; Benzoic acid, 4-(bromomethyl)-3-chloro-, ethyl ester; 4-Bromomethyl-3-chlorobenzoic Acid Ethyl Ester; Ethyl 3-Chloro-4-(bromomethyl)benzoate; 133486-61-0; AI3-52362
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-(Bromomethyl)-3-Chloro-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.