Description

Methyl 2-(tert-Butoxycarbonyl(Methyl) Amino)Acetate is a protected amino acid ester derivative, serving as a versatile and high-purity building block in advanced organic synthesis. Its core value lies in providing a reactive ester group and a Boc-protected tertiary amine, enabling efficient peptide coupling and the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and fine chemicals where precise molecular control is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of peptide mimetics, protease inhibitors, and novel drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides that require specific chiral or protected amino acid motifs.
• Peptide Chemistry: Serves as a protected amino acid ester in solid-phase and solution-phase peptide synthesis (SPPS).
• Linker & Spacer Molecule: Employed in bioconjugation and the development of antibody-drug conjugates (ADCs) and prodrugs.
• Organic Synthesis Reagent: A valuable precursor for introducing the N-Boc-N-methyl glycine moiety into more complex molecules.
• Research & Development: Critical for medicinal chemistry programs in academic and industrial R&D labs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Methyl 2-(tert-Butoxycarbonyl(Methyl) Amino)Acetate
CAS No.	133297-44-6
Molecular Formula	C9H17NO4
Molecular Weight	203.24 g/mol
Synonyms	N-Boc-N-methylglycine methyl ester; Methyl N-(tert-butoxycarbonyl)-N-methylglycinate; Boc-N-methyl-glycine-OMe; N-Methyl-N-(Boc)glycine methyl ester; (tert-Butoxycarbonylmethylamino)acetic acid methyl ester; 2-[(tert-Butoxycarbonyl)(methyl)amino]acetic acid methyl ester; Methyl (N-Boc-N-methyl)aminoacetate; Boc-MeGly-OMe
EINECS	Contact for details

Quality Control

Our Methyl 2-(tert-Butoxycarbonyl(Methyl) Amino)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.