Description

Ethyl 2-Hydroxy-3-Nitro-2-Phenylpropanoate is a specialized organic ester compound featuring a nitro-substituted phenylpropanoate structure, serving as a valuable chiral building block and synthetic intermediate. Its molecular architecture, combining hydroxy, nitro, and ester functionalities, makes it a versatile precursor for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and production in pharmaceutical chemistry, agrochemical development, and advanced material science, where precise molecular construction is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of β-amino acids, nitric oxide synthase inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and plant growth regulators that require nitro-aromatic precursors.
• Organic Synthesis Research: Serves as a model substrate in methodological studies for nitro-aldol (Henry) reactions and other C-C bond-forming transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and performance materials where its specific functional groups are incorporated.
• Academic & Industrial R&D: Utilized in laboratories for investigating reaction mechanisms and developing new catalytic processes.

Basic Information

Product Name	Ethyl 2-Hydroxy-3-Nitro-2-Phenylpropanoate
CAS No.	133153-67-0
Molecular Formula	C11H13NO5
Molecular Weight	239.23 g/mol
Synonyms	Ethyl 2-Hydroxy-3-nitro-2-phenylpropionate; 2-Hydroxy-3-nitro-2-phenylpropionic Acid Ethyl Ester; Ethyl α-Hydroxy-β-nitrohydrocinnamate; NSC 405124; Ethyl 2-Phenyl-2-hydroxy-3-nitropropanoate; β-Nitro-α-hydroxybenzenepropanoic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Hydroxy-3-Nitro-2-Phenylpropanoate is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) detailing key parameters such as assay, chiral purity (if applicable), and impurity profiles. Our quality commitment aligns with cGMP principles where required, ensuring reliability for critical applications in pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Chiral Purity (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.