Description

n-[4-[Bis(2-Chloroethyl)Amino]Phenyl]-4-(Quinolin-4-Ylamino)Benzamide Hydrochloride is a specialized, high-purity chemical compound designed for advanced research and development. This compound matters for its role as a key intermediate or active component in the synthesis of novel therapeutic agents, particularly in oncology research. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on developing targeted cancer therapies and studying DNA-alkylating agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel chemotherapeutic agents and targeted cancer drugs.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of action related to DNA alkylation and cell cycle inhibition.
• Bioconjugate Development: Employed in the research and development of antibody-drug conjugates (ADCs) and other targeted delivery systems.
• Biochemical Tool Compound: Acts as a reference standard or probe in enzymatic assays and receptor binding studies within academic and industrial research settings.
• Preclinical Development: Utilized in the early-stage, non-clinical testing of potential new chemical entities (NCEs) for safety and efficacy profiling.

Basic Information

Product Name	n-[4-[Bis(2-Chloroethyl)Amino]Phenyl]-4-(Quinolin-4-Ylamino)Benzamide Hydrochloride
CAS No.	133041-56-2
Molecular Formula	C30H28Cl3N5O
Molecular Weight	581.93 g/mol
Synonyms	4-(Quinolin-4-ylamino)-N-[4-[bis(2-chloroethyl)amino]phenyl]benzamide hydrochloride; NSC 366140; Benzamide, N-[4-[bis(2-chloroethyl)amino]phenyl]-4-(4-quinolinylamino)-, hydrochloride (1:1); 4-(4-Quinolinylamino)-N-[4-[bis(2-chloroethyl)amino]phenyl]benzamide monohydrochloride; 133041-56-2 (CAS); Quinoline benzamide derivative hydrochloride; DNA alkylator intermediate hydrochloride salt
EINECS	Contact for details

Quality Control

Our n-[4-[Bis(2-Chloroethyl)Amino]Phenyl]-4-(Quinolin-4-Ylamino)Benzamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.