Description

n-[4-[4-[Bis(2-Chloroethyl)Amino]Phenyl]Sulfanylphenyl]Quinolin-4-Amin E Hydrochloride CAS NO 133041-55-1 is a specialized, high-purity chemical intermediate of significant interest in advanced pharmaceutical research and development. Its complex molecular structure, featuring a quinoline core linked to a nitrogen mustard moiety via a thioether bridge, makes it a valuable precursor for synthesizing targeted therapeutic agents. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel anti-cancer and cytostatic compounds, where precise chemical architecture is critical for biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of experimental anti-cancer agents and targeted therapies.
• Biomedical Research: Used in academic and industrial laboratories for studying structure-activity relationships (SAR) of nitrogen mustard derivatives.
• Preclinical Development: Employed in the early-stage development of novel chemotherapeutic candidates and prodrugs.
• Chemical Biology: Acts as a tool compound for investigating DNA alkylation mechanisms and cellular response pathways.
• Specialty Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex, biologically active molecules for screening libraries.

Basic Information

Product Name	n-[4-[4-[Bis(2-Chloroethyl)Amino]Phenyl]Sulfanylphenyl]Quinolin-4-Amin E Hydrochloride
CAS No.	133041-55-1
Molecular Formula	C27H26Cl3N3S
Molecular Weight	522.94 g/mol
Synonyms	4-((4-((Bis(2-chloroethyl)amino)phenyl)thio)phenyl)amino)quinoline hydrochloride; Quinoline-4-amine, N-[4-[[4-[bis(2-chloroethyl)amino]phenyl]thio]phenyl]-, hydrochloride; 133041-55-1; 4-[[4-[Bis(2-chloroethyl)amino]phenyl]sulfanyl]-N-quinolin-4-ylaniline hydrochloride; Nitrogen mustard quinoline derivative hydrochloride
EINECS	Contact for details

Quality Control

Our n-[4-[4-[Bis(2-Chloroethyl)Amino]Phenyl]Sulfanylphenyl]Quinolin-4-Amin E Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for research integrity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.