Description

N(1)-(Azidobenzamidino)Spermine is a specialized, polyamine-based chemical building block featuring a reactive azido group. This compound matters for its unique bifunctional structure, enabling its use as a versatile linker in advanced bioconjugation and chemical biology research. It is primarily needed by pharmaceutical R&D teams and life science researchers developing targeted drug delivery systems, diagnostic probes, and novel biochemical tools.

Application

• Bioconjugation Reagent: Acts as a critical linker for attaching targeting molecules (e.g., antibodies, peptides) to drug payloads or imaging agents via click chemistry.
• Chemical Biology Probe Development: Used in the synthesis of probes for studying polyamine transport systems and cellular uptake mechanisms.
• Pharmaceutical Research: Serves as a key intermediate in the development of novel therapeutic conjugates, particularly in oncology and targeted therapy.
• Diagnostic Agent Synthesis: Employed in creating contrast agents or radiolabels for diagnostic imaging applications.
• Material Science Functionalization: Used to introduce reactive azide groups onto surfaces or polymers for further modification.
• Academic Research: A valuable tool in university and institutional labs for fundamental studies on cell signaling and molecular recognition.

Basic Information

Product Name	N(1)-(Azidobenzamidino)Spermine
CAS No.	133009-20-8
Molecular Formula	C23H34N10
Molecular Weight	450.59 g/mol
Synonyms	N1-(4-Azidobenzamidino)spermine; Azidobenzamidinospermine; 4-Azido-N'-(3-aminopropyl)-N-(3-{[4-(3-aminopropylamino)butyl]amino}propyl)benzimidamide; Sper-Azide; Azido-Benzamidine-Spermine Conjugate; N1-(p-Azidobenzamidino)spermine
EINECS	Contact for details

Quality Control

Our N(1)-(Azidobenzamidino)Spermine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and degradation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.