Description

Carbamic Acid, Cyclopropyl-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organic compound belonging to the carbamate class, serving as a crucial building block in advanced organic synthesis. Its primary value lies in its role as a protected amine synthon, enabling the controlled introduction of the cyclopropylamine moiety into complex molecular architectures under mild conditions. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing cyclopropylamine groups, which are prevalent in various therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and fungicides where the cyclopropyl ring confers specific biological activity and stability.
• Organic Synthesis Reagent: Acts as a versatile protected amine source in multi-step synthetic routes for complex natural products, fine chemicals, and functional materials.
• Chemical Research & Development: A valuable tool in medicinal chemistry for structure-activity relationship (SAR) studies and the exploration of new chemical entities in drug discovery programs.
• Peptide Mimetics: Employed in the design and synthesis of peptide analogs and mimetics, where the carbamate group provides stability and the cyclopropyl group introduces conformational constraint.

Basic Information

Product Name	Carbamic Acid, Cyclopropyl-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	132844-48-5
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	tert-Butyl N-cyclopropylcarbamate; N-(tert-Butoxycarbonyl)cyclopropylamine; N-Boc-cyclopropylamine; Cyclopropylcarbamic Acid tert-Butyl Ester; 1,1-Dimethylethyl Cyclopropylcarbamate; N-Cyclopropyl-O-tert-butylcarbamate; Boc-Cyclopropylamine; BOC-CPA
EINECS	Contact for details

Quality Control

Our Carbamic Acid, Cyclopropyl-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is subjected to rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.