Description

(S)-3-Cyano-3-Hydroxy-Propionic Acid Ethyl Ester CAS NO 132839-91-9 is a high-value chiral building block and synthetic intermediate. This compound is crucial for the enantioselective synthesis of complex molecules, particularly in the pharmaceutical industry. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), including statins and other cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a versatile precursor for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Asymmetric Catalysis Research: A valuable substrate for developing and testing new chiral catalysts and synthetic methodologies in academic and industrial R&D.
• Bioconjugate Chemistry: Utilized in the synthesis of labeled compounds and probes for biochemical and diagnostic applications.
• Polymer Modification: Can be incorporated as a functional monomer to introduce cyano and ester groups into polymer chains for specialized material properties.

Basic Information

Product Name	(S)-3-Cyano-3-Hydroxy-Propionic Acid Ethyl Ester
CAS No.	132839-91-9
Molecular Formula	C6H9NO3
Molecular Weight	143.14 g/mol
Synonyms	(S)-Ethyl 3-Cyano-3-hydroxypropanoate; (S)-3-Hydroxy-3-cyanopropionic Acid Ethyl Ester; (S)-Ethyl 3-Hydroxy-3-cyanopropionate; (S)-3-Hydroxy-3-cyano-propionic Acid Ethyl Ester; (S)-3-Cyano-3-hydroxypropanoic Acid Ethyl Ester; (S)-3-Hydroxy-3-cyanopropanoic Acid Ethyl Ester; (S)-CHPEE; (S)-HCPEE
EINECS	Contact for details

Quality Control

Our (S)-3-Cyano-3-Hydroxy-Propionic Acid Ethyl Ester is produced under strict quality management systems. We offer material suitable for pharmaceutical R&D and process chemistry, with typical purity levels exceeding 98% (by HPLC). Certificates of Analysis (COA) are provided with each batch, detailing chiral purity (enantiomeric excess), chemical purity, and relevant physical parameters. Our quality commitment ensures reliable performance and consistency for your critical synthetic steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.