Description

Norvaline, n-Acetyl-5-Hydroxy-, Methyl Ester is a specialized, high-purity synthetic amino acid derivative. This compound serves as a critical building block and chiral intermediate in advanced organic synthesis, enabling the production of complex molecules with precise stereochemistry. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active ingredients and biochemical probes.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in peptide mimetics and enzyme inhibitors.
• Biochemical Research: Used as a modified amino acid analog in metabolic pathway studies and proteomics research.
• Peptide Synthesis: Serves as a protected and activated derivative for the solid-phase and solution-phase synthesis of custom peptides with specific functional groups.
• Agrochemical Development: Intermediate in the synthesis of advanced, biologically active compounds for crop protection.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic routes in organic chemistry laboratories.

Basic Information

Product Name	Norvaline, n-Acetyl-5-Hydroxy-, Methyl Ester
CAS No.	132759-54-7
Molecular Formula	C9H15NO5
Molecular Weight	217.22 g/mol
Synonyms	Methyl N-acetyl-5-hydroxynorvalinate; 5-Hydroxy-N-acetylnorvaline methyl ester; Methyl 2-acetamido-5-hydroxypentanoate; 2-Acetamido-5-hydroxypentanoic acid methyl ester; N-Acetyl-5-hydroxy-norvaline methyl ester; Ac-5-Hydroxy-Nva-OMe; (S)-Methyl 2-acetamido-5-hydroxypentanoate (if stereospecific)
EINECS	Contact for details

Quality Control

Every batch of our Norvaline, n-Acetyl-5-Hydroxy-, Methyl Ester is manufactured under strict quality management systems. We guarantee high chemical purity and consistent lot-to-lot performance, supported by comprehensive analytical testing including HPLC, NMR, and chiral analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.