Description

4-Fluorobenzyl Isocyanate is a versatile aromatic isocyanate building block used in the synthesis of advanced chemical intermediates. Its value lies in the reactivity of the isocyanate group, which readily forms ureas, carbamates, and other functional groups, enabling the creation of novel compounds with tailored properties. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing polyurethanes, polyureas, and other specialty polymers with specific thermal or chemical resistance properties.
• Chemical Research & Development: A critical reagent in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of novel compound libraries.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized colorants and functional dyes.
• Liquid Crystal & OLED Material Precursor: Used to create advanced organic electronic materials.

Basic Information

Product Name	4-Fluorobenzyl Isocyanate
CAS No.	132740-43-3
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	p-Fluorobenzyl Isocyanate; (4-Fluorophenyl)methyl Isocyanate; 1-Isocyanatomethyl-4-fluorobenzene; 4-Fluorobenzyl Isocyanat; 4-Fluorobenzylisocyanate; 4-Fluorobenzyl Isocyanate (stabilized with TBC); α-Isocyanato-4-fluorotoluene
EINECS	Contact for details

Quality Control

Our 4-Fluorobenzyl Isocyanate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (IR, NMR), to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) or as specified for the specific grade. This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as water, alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.