Description

4-Isoxazolecarboxylic Acid, 3-Acetyl-4,5-Dihydro-, Methyl Ester (9Ci) is a specialized heterocyclic building block with significant synthetic utility. This compound serves as a versatile intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for its role in medicinal chemistry and advanced organic synthesis. The compound, identified by CAS No. 132659-36-0, is supplied to meet the stringent purity and consistency requirements of industrial-scale process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the isoxazole ring's bioactivity.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers and specialty coatings.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and medicinal chemistry.
• Chemical Synthesis: Acts as a versatile synthon for further functionalization, enabling access to a diverse library of isoxazole derivatives.

Basic Information

Product Name	4-Isoxazolecarboxylic Acid, 3-Acetyl-4,5-Dihydro-, Methyl Ester (9Ci)
CAS No.	132659-36-0
Molecular Formula	C7H9NO4
Molecular Weight	171.15 g/mol
Synonyms	Methyl 3-acetyl-4,5-dihydroisoxazole-4-carboxylate; 3-Acetyl-4,5-dihydro-4-isoxazolecarboxylic acid methyl ester; 4,5-Dihydro-3-acetyl-4-isoxazolecarboxylic acid methyl ester; Methyl 3-acetyldihydroisoxazole-4-carboxylate; 4-Carbomethoxy-3-acetyl-4,5-dihydroisoxazole; 3-Acetyl-4,5-dihydroisoxazole-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of 4-Isoxazolecarboxylic Acid, 3-Acetyl-4,5-Dihydro-, Methyl Ester (9Ci) adheres to a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP guidelines for advanced pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.