Description

Isophosphamide Bromide Mustard is a specialized alkylating agent derivative, primarily utilized as a key intermediate in advanced pharmaceutical synthesis. Its core value lies in enabling the development and production of targeted therapeutic agents, particularly in oncology research. This compound is essential for R&D laboratories, process development chemists, and manufacturers within the global pharmaceutical and fine chemical industries seeking high-purity synthetic building blocks.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel chemotherapeutic agents and targeted cancer therapies.
• Antineoplastic Agent Research: Used in academic and industrial R&D for developing new alkylating agents with improved efficacy and reduced side-effect profiles.
• Bioconjugation & ADC Development: Employed in the creation of antibody-drug conjugates (ADCs) and other targeted drug delivery systems due to its reactive mustard group.
• Medicinal Chemistry: A valuable building block for structure-activity relationship (SAR) studies and the optimization of lead compounds in oncology.
• Process Chemistry & Scale-up: Used in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Biochemical Research: Applied in studies investigating DNA alkylation mechanisms and cellular response to genotoxic stress.

Basic Information

Product Name	Isophosphamide Bromide Mustard
CAS No.	132633-97-7
Molecular Formula	C7H15Br2ClN2O2P
Molecular Weight	394.44 g/mol
Synonyms	1-Bromo-2-[bis(2-bromoethyl)amino]ethyl dihydrogen phosphate; NSC 109724; Cyclophosphamide mustard bromide analog; Ifosfamide mustard bromide; 2-[Bis(2-bromoethyl)amino]ethyl dihydrogen phosphate; Phosphoramide mustard bromide derivative
EINECS	Contact for details

Quality Control

Our Isophosphamide Bromide Mustard is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a controlled environment to maintain stability. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.