Description

Cyclopropanecarboxylic Acid, 2-(Aminomethyl)-2-Methyl-, Methyl Ester, trans- is a specialized chiral building block featuring a cyclopropane ring and an amino ester functional group. This compound is valued for its rigid, three-membered ring structure, which is strategically used to modulate the conformation, metabolic stability, and potency of target molecules in advanced pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the cyclopropane moiety can enhance biological activity.
• Chemical Biology Probe Development: Serves as a scaffold for designing molecular probes to study enzyme function and receptor interactions.
• Peptidomimetics: Incorporated into peptide analogs to introduce conformational constraints and improve pharmacokinetic properties.
• Asymmetric Synthesis: Employed as a starting material or intermediate in stereoselective catalytic processes to construct complex molecules.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(Aminomethyl)-2-Methyl-, Methyl Ester, trans-
CAS No.	132592-87-1
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	trans-2-(Aminomethyl)-2-methylcyclopropanecarboxylic acid methyl ester; Methyl trans-2-(aminomethyl)-2-methylcyclopropanecarboxylate; (1R,2S)-2-(Aminomethyl)-2-methylcyclopropanecarboxylic acid methyl ester; (1S,2R)-2-(Aminomethyl)-2-methylcyclopropanecarboxylic acid methyl ester; 2-Methyl-2-(aminomethyl)cyclopropanecarboxylic acid methyl ester, trans-; ACC 9650; AGN-PC-0GNV6P; trans-Cyclopropane amino ester
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-(Aminomethyl)-2-Methyl-, Methyl Ester, trans- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for research and process chemistry. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.