Description

1,5-Anhydro-2,3-Dideoxy-6-o-[(1,1-Dimethylethyl)Dimethylsilyl]-D-Erythro-Hex-2-Enitol is a sophisticated, silyl-protected carbohydrate derivative that serves as a critical chiral building block and synthetic intermediate. Its value lies in enabling precise stereochemical control in the synthesis of complex bioactive molecules, particularly nucleoside analogs and other pharmacologically active compounds. This high-purity intermediate is essential for research and development teams in the pharmaceutical and biotechnology sectors, where it is used to streamline synthetic routes and develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel nucleoside and nucleotide analogs with antiviral or anticancer activity.
• Antiviral Drug Development: Used in research for constructing the sugar backbone of potential antiviral agents targeting viruses like HIV, HCV, and herpes.
• Carbohydrate Chemistry Research: Serves as a protected intermediate for studying glycosylation reactions and synthesizing complex oligosaccharides.
• Prodrug Synthesis: Employed in the design and synthesis of prodrugs to enhance the bioavailability and targeting of active pharmaceutical ingredients.
• Chemical Biology Probes: Utilized to create labeled or modified sugar molecules for investigating biological pathways and enzyme mechanisms.
• Process Chemistry & Scale-up: Provides a reliable, high-quality starting material for optimizing and scaling synthetic routes from laboratory to pilot plant.

Basic Information

Product Name	1,5-Anhydro-2,3-Dideoxy-6-o-[(1,1-Dimethylethyl)Dimethylsilyl]-D-Erythro-Hex-2-Enitol
CAS No.	132375-36-1
Molecular Formula	C13H26O3Si
Molecular Weight	258.43 g/mol
Synonyms	1,5-Anhydro-2,3-dideoxy-6-O-[(1,1-dimethylethyl)dimethylsilyl]-D-erythro-hex-2-enitol; 6-O-(tert-Butyldimethylsilyl)-1,5-anhydro-2,3-dideoxy-D-erythro-hex-2-enitol; TBDMS-protected 1,5-anhydrohexenitol; (3R,4R,5R)-4-[(tert-Butyldimethylsilyl)oxy]-5-(hydroxymethyl)-3,4-dihydro-2H-pyran; A protected glycals derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1,5-Anhydro-2,3-Dideoxy-6-o-[(1,1-Dimethylethyl)Dimethylsilyl]-D-Erythro-Hex-2-Enitol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for advanced synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.