Description

Fura 2 Magnesium-Selective Analog Tetrapotassium Salt is a high-purity, cell-permeant fluorescent indicator specifically designed for the selective detection and quantification of intracellular magnesium ions (Mg²⁺). This compound matters because it provides researchers with a critical tool for studying magnesium homeostasis, signaling, and its role in cellular physiology and pathology with high sensitivity and selectivity. It is essential for life science researchers, pharmaceutical developers, and diagnostic manufacturers engaged in neuroscience, cardiology, and metabolic disorder research.

Application

• Intracellular Magnesium Ion Imaging: Primary application for real-time visualization and measurement of free Mg²⁺ concentrations in live cells using fluorescence microscopy (e.g., rationetric imaging).
• Neuroscience Research: Investigation of magnesium's role in neurotransmitter release, neuronal excitability, and its neuroprotective effects.
• Cardiovascular Research: Study of magnesium ion dynamics in cardiac myocytes, including its regulation of ion channels and contractility.
• Metabolic & Biochemical Studies: Monitoring Mg²⁺ fluctuations in enzymatic reactions, ATP metabolism, and cellular energy status.
• Drug Discovery & Screening: Used in high-throughput assays to identify compounds that modulate intracellular magnesium levels for therapeutic potential.
• Diagnostic Assay Development: A key component in the development of in vitro diagnostic kits for assessing magnesium-related physiological states.

Basic Information

Product Name	Fura 2 Magnesium-Selective Analog Tetrapotassium Salt
CAS No.	132319-57-4
Molecular Formula	C₂₉H₂₀K₄N₃O₁₅
Molecular Weight	821.89 g/mol
Synonyms	Fura-2, Magnesium salt, tetrapotassium; Fura 2, Mg²⁺ selective analog, K⁺ salt; 2-[6-[Bis(carboxymethyl)amino]-5-[2-[2-[bis(carboxymethyl)amino]-5-methylphenoxy]ethoxy]-2-benzofuranyl]-5-oxazolecarboxylic acid, tetrapotassium salt; Magnesium Green™ analog; Intracellular magnesium indicator; Fura-2 Mg²⁺ salt
EINECS	Contact for details

Quality Control

Our Fura 2 Magnesium-Selective Analog Tetrapotassium Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance in sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectrophotometric analysis for correct spectral properties, and functional validation in cell-based assays. A detailed Certificate of Analysis (COA) documenting identity, purity, and performance specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Off-white to yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Fluorescence Properties	Excitation/Emission maxima consistent with Mg²⁺-bound form
Functional Activity	Suitable for intracellular Mg²⁺ imaging

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.